The Five Stages of Intoxication: Understanding the Effects of Alcohol on the Body
At a BAC level of 0.45% or greater, severe and irreversible damage is sustained to the internal organ systems. This grim reality underscores the lethal potential of excessive alcohol consumption. As tolerance increases, it can become increasingly difficult to reach this euphoric state with the same amount of alcohol, prompting individuals to drink more heavily. This highlights why does being drunk feel good for many, and how that sensation can drive problematic use.
It also activates the brain’s reward center, releasing dopamine, which contributes to feelings of pleasure and reinforces drinking behavior. While having a drink from time to time is unlikely to cause health problems, moderate or heavy drinking can impact the brain. The Stages of Intoxication Chart is a visual representation that shows the different levels of impairment caused by alcohol consumption. It helps people understand the effects of alcohol and identify different levels of intoxication. Sometimes you’ll hear people talk about the “stages” of intoxication, first described by Kurt Dubowski in 1957.
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Mood swings are a common occurrence for individuals seeking psychiatric help for alcoholism. These include feelings of highs-and-lows, similarly described as a rollercoaster of emotions. Stage 4 typically refers to full dependence, where drinking is compulsive, health deteriorates rapidly, and stopping without medical support may be life-threatening. Alcohol-induced blackouts are also a common part of this stage and may result in large amounts of time lost, such as several hours or even Drug rehabilitation an entire day.
Simultaneously, it inhibits glutamate, which has excitatory effects, further contributing to the depressant effects of alcohol. Alcohol enhances the effects of GABA, which has inhibitory properties, leading to feelings of relaxation and sedation. When alcohol enters the bloodstream, it travels to the brain, where it affects neurotransmitters—chemical messengers that transmit signals between nerve cells. Anyone who drinks heavily should know the health risks ahead of time— as well as how to get help for an alcohol problem.
#6. Coma
A person’s intoxication level is measured by their blood alcohol concentration (BAC). When people drink alcohol, it passes through the stomach and into the small intestine. The correlation between alcoholism and bipolar disorder is not fully understood; however, certain factors play a role in determining individuals who are affected by co-occurring conditions. It should be said that alcoholism does not cause bipolar disorder. Instead, those who have bipolar disorder are more susceptible to developing alcoholism.
Stage 4: Confusion
These findings typically manifest as the patient is recovering from the initial intoxication. Cranial nerves II, V, VII, VIII, IX, X, and XII are most commonly involved. The manifestations of ethanol intoxication depend on both the serum concentration and the individual's pattern of ethanol use. Thus, a person who consumes large amounts of ethanol on a daily basis may appear sober at the same serum ethanol level at which a novice drinker exhibits cerebellar dysfunction. Is a licensed and practicing pharmacist and medical writer who specializes in different substances, the effects of substance abuse, and substance use disorder. Some people, especially inexperienced drinkers, may become intoxicated at lower BACs.
BetterHelp offers affordable mental health care via phone, video, or live-chat. The level of intoxication depends on how much alcohol has been consumed. At a BAC of 0.45 or above, you are likely to die from alcohol intoxication. Excessive alcohol use causes approximately 88,000 deaths annually in the United States, according to the Centers for Disease Control and Prevention (CDC).
Examination findings correlate with the signs and symptoms, as previously described. Thus, the patient may present simply inebriated or progressively more acidotic as acute kidney injury, cardiovascular dysfunction, and coma develop. Unlike ethanol or isopropanol, methanol does not cause nearly as much of an inebriated state. If a patient has coingested ethanol, signs or symptoms specific to methanol intoxication are delayed. A patient who has ingested isopropanol may not have any specific complaints.


The amygdala, which is the brain’s stress system, becomes active. It triggers people to seek out drugs regularly in an attempt to achieve the same feeling. This stage starts in an stages of intoxication area of the brain called the basal ganglia. It involves an intense rush of pleasure as the drugs activate the brain’s dopamine system. Some of these illicit substances can also lead to tolerance within one or two uses. Nevertheless, in most cases, all these steps are part of the chronic cycle of addiction.
People who are left to “sleep it off” may end up experiencing hazardously slowed breathing or complete respiratory arrest, or they may aspirate on their own vomit. It affects the levels of serotonin produced due to its depressant effects. Although you may not feel the worsened effects of anxiety while under the influence, you will feel it once your inebriated state has worn off. As others begin to realize you may have a drinking problem, you start to realize it too, although you may still be in denial. And frequently, alcohol intoxication, road traffic accidents, and poisoning are treated in emergency rooms across the nation.
If alcohol is consumed in large enough quantities, or for long periods of time, those initial feel-good responses powerfully trigger feelings of pleasure and reward. This profound activation of the reward system can dramatically increase the desire for alcohol, progressively leading to dependence and, ultimately, addiction. The brain’s reward center is also activated when users drink to minimize the negative, painful effects of withdrawal, reinforcing the cycle. The brain essentially becomes “trained” to depend on alcohol for the production of those feel-good endorphins and for maintaining chemical balance. And, as more alcohol is consumed over time, the brain’s tolerance for reaching those “positive” effects increases. More and more alcohol is needed before the brain’s reward center is satisfied, fueling a dangerous spiral of increased consumption.
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- The DSM-5 criteria allow for a broader range of symptoms and a more nuanced understanding of individuals’ experiences.
- If vision is impaired, the pupils may be dilated and minimally reactive or unreactive to light.
- When we drink faster than the liver can metabolize, we grow increasingly intoxicated.
Treatment Options: What Treatment Options are Available for Alcohol Use Disorder in St. Louis?
In the United States alone, an estimated 29.5 million people ages 12 and older have had AUD in the past year, highlighting the need for widespread awareness and accessible treatment options. These statistics underscore the importance of understanding AUD as more than an individual struggle; it’s a societal challenge requiring community-wide efforts. Once we get beyond 0.08% BAC, we enter potentially dangerous territory.
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